DominoEffect

Identification and Annotation of Protein Hotspot Residues


Bioconductor version: Release (3.20)

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Author: Marija Buljan and Peter Blattmann

Maintainer: Marija Buljan <marija.buljan.2 at gmail.com>, Peter Blattmann <peter_blattmann at bluewin.ch>

Citation (from within R, enter citation("DominoEffect")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DominoEffect")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DominoEffect")
Vignette for DominoEffect package HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, Proteomics, SequenceMatching, Software, SomaticMutation
Version 1.26.0
In Bioconductor since BioC 3.7 (R-3.5) (6.5 years)
License GPL (>= 3)
Depends R (>= 3.5)
Imports biomaRt, data.table, utils, stats, Biostrings, pwalign, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods
System Requirements
URL
See More
Suggests knitr, testthat, rmarkdown
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DominoEffect_1.26.0.tar.gz
Windows Binary (x86_64) DominoEffect_1.26.0.zip
macOS Binary (x86_64) DominoEffect_1.26.0.tgz
macOS Binary (arm64) DominoEffect_1.26.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DominoEffect
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DominoEffect
Bioc Package Browser https://code.bioconductor.org/browse/DominoEffect/
Package Short Url https://bioconductor.org/packages/DominoEffect/
Package Downloads Report Download Stats